First off I would suggest picking a word-press theme that suits your blog style, for instance if you are writing about a singular niche subject like Depression. Do you need a store front type theme?

No is my answer, you are looking to engage readers from the start and the way I've created my blog page is the landing page is my latest blog posts can be viewed.

Choose a theme that is mobile responsive, clean and easy to use for simply blogging purposes. I would in all honesty avoid themes with all the bells and whistles on ass this will just complicate the matter and distract you from your intended subject.